Identification and regulation of fusA , the polyketide synthase gene 4 responsible for fusarin production in Fusarium fujikuroi 5 6 7 8
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چکیده
1 2 3 Identification and regulation of fusA, the polyketide synthase gene 4 responsible for fusarin production in Fusarium fujikuroi 5 6 7 8 Violeta Díaz-Sánchez, Javier Avalos and M. Carmen Limón* 9 10 Department of Genetics, Faculty of Biology, University of Seville, E-41012 Seville, Spain. 11 12 13 Running title: Fusarin production in F. fujikuroi 14 15 16 17 *Corresponding author. Mailing address: Departamento de Genética, Universidad de 18 Sevilla, Apartado 1095, E–41080 Sevilla, Spain. Phone: +34-954557110. Fax: +3419 954557104. E-mail: [email protected] 20 21 22 23 Copyright © 2012, American Society for Microbiology. All Rights Reserved. Appl. Environ. Microbiol. doi:10.1128/AEM.01552-12 AEM Accepts, published online ahead of print on 3 August 2012
منابع مشابه
Identification and regulation of fusA, the polyketide synthase gene responsible for fusarin production in Fusarium fujikuroi.
Fusarins are a class of mycotoxins of the polyketide family produced by different Fusarium species, including the gibberellin-producing fungus Fusarium fujikuroi. Based on sequence comparisons between polyketide synthase (PKS) enzymes for fusarin production in other Fusarium strains, we have identified the F. fujikuroi orthologue, called fusA. The participation of fusA in fusarin biosynthesis w...
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Fusarium fujikuroi produces a variety of secondary metabolites, of which polyketides form the most diverse group. Among these are the highly pigmented naphthoquinones, which have been shown to possess different functional properties for the fungus. A group of naphthoquinones, polyketides related to fusarubin, were identified in Fusarium spp. more than 60 years ago, but neither the genes respons...
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The heterothallic ascomycete Fusarium fujikuroi is a notorious rice pathogen causing super-elongation of plants due to the production of terpene-derived gibberellic acids (GAs) that function as natural plant hormones. Additionally, F. fujikuroi is able to produce a variety of polyketide- and non-ribosomal peptide-derived metabolites such as bikaverins, fusarubins and fusarins as well as metabol...
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Background: Identification and quantification of mycotoxins produced by Fusarium species are important in controlling fungal diseases. Objectives: Potential of zearalenone, butenolide and fusarin C production was investigated in five Fusarium graminearum and five F. culmorum isolates at molecular level. Materials and Methods: Presence of PKS13, FG08079.1 and PKS10 genes, associated with produ...
متن کاملDeciphering the Cryptic Genome: Genome-wide Analyses of the Rice Pathogen Fusarium fujikuroi Reveal Complex Regulation of Secondary Metabolism and Novel Metabolites
The fungus Fusarium fujikuroi causes "bakanae" disease of rice due to its ability to produce gibberellins (GAs), but it is also known for producing harmful mycotoxins. However, the genetic capacity for the whole arsenal of natural compounds and their role in the fungus' interaction with rice remained unknown. Here, we present a high-quality genome sequence of F. fujikuroi that was assembled int...
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تاریخ انتشار 2012